B-hNKP46 mice(C)

    BALB/cCrSlcNifdc-Ncr1tm1(NCR1)Bcgen/Bcgen • 112004

    B-hNKP46 mice(C)

    Product nameB-hNKP46 mice(C)
    Catalog number112004
    Strain nameBALB/cCrSlcNifdc-Ncr1tm1(NCR1)Bcgen/Bcgen
    Strain backgroundBALB/cCrSlcNifdc
    NCBI gene ID (Human)
    AliasesLY94; CD335; NKP46; NK-p46

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    • Phenotypic analysis

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        Protein expression analysis

        Strain specific NKP46 expression analysis in wild-type and B-hNKP46 mice(C) by flow cytometry. Splenocytes were collected from BALB/c (+/+) and homozygous B-hNKP46 mice(C) (H/H), and analyzed by flow cytometry with species-specific NKP46 antibodies. Mouse NKP46 was detectable in wild-type mice. Human NKP46 was exclusively detectable in homozygous B-hNKP46 mice(C).

        Protein expression analysis in T and B cells of spleen

        Strain specific NKP46 expression analysis in wild-type and B-hNKP46 mice(C) by flow cytometry. Splenocytes were collected from BALB/c (+/+) and homozygous B-hNKP46 mice(C) (H/H), and analyzed by flow cytometry with species-specific NKP46 antibodies. Mouse NKP46 was not detectable in T and B cells of wild-type mice. Human NKP46 was not detectable in T and B cells of homozygous B-hNKP46 mice(C).

        Protein expression analysis in blood

        Strain specific NKP46 expression analysis in wild-type and B-hNKP46 mice(C) by flow cytometry. Blood cells were collected from BALB/c (+/+) and homozygous B-hNKP46 mice(C) (H/H), and analyzed by flow cytometry with species-specific NKP46 antibodies. Mouse NKP46 was detectable in wild-type mice. Human NKP46 was exclusively detectable in homozygous B-hNKP46 mice(C).

        Protein expression analysis in T and B cells of blood

        Strain specific NKP46 expression analysis in wild-type and B-hNKP46 mice(C) by flow cytometry. Blood cells were collected from BALB/c (+/+) and homozygous B-hNKP46 mice(C) (H/H), and analyzed by flow cytometry with species-specific NKP46 antibodies. Mouse NKP46 was not detectable in T and B cells of wild-type mice. Human NKP46 was not detectable in T and B cells of homozygous B-hNKP46 mice(C).

        * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hNKP46 mice(C)] (Cat# 112004) was purchased from Biocytogen.
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